TOPICS

2020

2021/1/18

Publications updated.
T. Shimakawa, K. Hagiwara, M. Inoue, "Total Synthesis of Talatisamine: Exploration of Convergent Synthetic Strategies," Bull. Chem. Soc. Jpn. in press.
DOI: 10.1246/bcsj.20200400
2021/1/8

Publications updated.
M. Nagatomo, M. Inoue, "Convergent Assembly of Highly Oxygenated Natural Products Enabled by Intermolecular Radical Reactions," Acc. Chem. Res. in press.
DOI: 10.1021/acs.accounts.0c00792
2020/12/17

Our paper "Divergent Solid-Phase Synthesis and Biological Evaluation of Yaku'amide B and Its Seven E/Z isomers" was selected as Hot Paper of Chemistry A European Journal.
2020/12/01

Assistant Prof. Itoh received "The Pharmaceutical Society of Japan Award for Young Scientists 2021".
Title: "Total synthesis and functional analysis of complex peptidic natural products and their artificial analogues" link
2020/11/20

Our paper "Unified Total Synthesis of Five Bufadienolides" was selected as most read articles of the month in Organic Letters.
2020/11/18

Our paper "Discovery of gramicidin A analogues with altered activities by multidimensional screening of a one-bead-one-compound library" was selected as Nature Communications Editors' Highlights. link
2020/10/27

Publications updated.
S. Shimizu, K. Hagiwara, H. Itoh, M. Inoue, "Unified Total Synthesis of Five Bufadienolides," Org. Lett. in press.
DOI: 10.1021/acs.orglett.0c03251
2020/10/7

Publications updated.
Koichi Kamiya, Kensuke Miura, Hiroaki Itoh, M. Inoue, "Divergent Solid‐Phase Synthesis and Biological Evaluation of Yaku’amide B and Its Seven E/Z Isomers," Chem. Eur. J. in press.
DOI: 10.1002/chem.202003858
2020/10/2

Publications updated.
M. Nagatomo, K. Zhang, H. Fujino, M. Inoue, "Et3B/Et2AlCl/O2‐Mediated Radical Coupling Reaction between α‐Alkoxyacyl Tellurides and 2‐Hydroxybenzaldehyde Derivatives," Chem. Asian. J. in press.
DOI: 10.1002/asia.202001090
2020/10/1

Publications updated.
Y. Takada, H. Itoh, A. Paudel, S. Panthee, H. Hamamoto, K. Sekimizu, M. Inoue, "Discovery of gramicidin A analogues with altered activities by multidimensional screening of a one-bead-one-compound library," Nat. Commun. 2020, 11, 4935.
DOI: 10.1038/s41467-020-18711-2
2020/9/9

Takumi Fukuda (G4) received Presentation Award at the 18th Symposium on Organic Chemistry -the Next Generation-. Title: "Convergent Total Synthesis of Hikizimycin"
2020/8/6

Publications updated.
T. Fukuda, M. Nagatomo, M. Inoue, "Total Synthesis of Diospyrodin and Its Three Diastereomers," Org. Lett. in press.
DOI: 10.1021/acs.orglett.0c02280
2020/7/11

Publications updated.
K. Minagawa, D. Kamakura, K. Hagiwara, M. Inoue, "Construction of the ABCE-ring structure of talatisamine via decarboxylative radical cyclization," Tetrahedron in press.
DOI: 10.1016/j.tet.2020.131385
2020/7/8

Dr. Haruka Fujino, a graduate from our laboratory, was chosen as one of the finalists of The Reaxys PhD Prize 2020. link
2020/7/7

Publications updated.
H. Fujino, T. Fukuda, M. Nagatomo, M. Inoue, "Convergent Total Synthesis of Hikizimycin Enabled by Intermolecular Radical Addition to Aldehyde," J. Am. Chem. Soc. in press.
DOI: 10.1021/jacs.0c06354
2020/6/5

Publications updated.
M. Inoue, K. Tokumoto, T. Kaji, H. Itoh, "Design, Construction, and Screening of a One-Bead-One-Compound Library for Discovery of Potent Analogues of Antibiotic Lysocin E," MEDCHEM NEWS 2020, 30 (2), 84-88.
2020/2/1

Publications updated.
J. Mao, H. Itoh, K. Sakurai, M. Inoue, "Phospholipid-Dependent Functions of a Macrocyclic Analogue of the Ion-Channel-Forming Antibiotic Gramicidin A," Chem. Pharm. Bull.2020, 68, 173.
DOI: 10.1248/cpb.c19-00967
2020/1/27

Dr. Kamakura recieved a presentation award at 61st Symposium on the Chemistry of Natural Products. Title: Total Synthesis of Talatisamine
2020/1/13

Publications updated.
H. Itoh, K. Miura, K. Kamiya, T. Yamashita, M. Inoue, "Solid‐Phase Total Synthesis of Yaku’amide B Enabled by Traceless Staudinger Ligation," Angew. Chem. Int. Ed. in press.
DOI: 10.1002/anie.201916517