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2020

  • 2021/1/18

    Publications updated.
    T. Shimakawa, K. Hagiwara, M. Inoue, "Total Synthesis of Talatisamine: Exploration of Convergent Synthetic Strategies," Bull. Chem. Soc. Jpn. in press.
    DOI: 10.1246/bcsj.20200400

  • 2021/1/8

    Publications updated.
    M. Nagatomo, M. Inoue, "Convergent Assembly of Highly Oxygenated Natural Products Enabled by Intermolecular Radical Reactions," Acc. Chem. Res. in press.
    DOI: 10.1021/acs.accounts.0c00792

  • 2020/12/17

    Our paper "Divergent Solid-Phase Synthesis and Biological Evaluation of Yaku'amide B and Its Seven E/Z isomers" was selected as Hot Paper of Chemistry A European Journal.

  • 2020/12/01

    Assistant Prof. Itoh received "The Pharmaceutical Society of Japan Award for Young Scientists 2021".
    Title: "Total synthesis and functional analysis of complex peptidic natural products and their artificial analogues" link

  • 2020/11/20

    Our paper "Unified Total Synthesis of Five Bufadienolides" was selected as most read articles of the month in Organic Letters.

  • 2020/11/18

    Our paper "Discovery of gramicidin A analogues with altered activities by multidimensional screening of a one-bead-one-compound library" was selected as Nature Communications Editors' Highlights. link

  • 2020/10/27

    Publications updated.
    S. Shimizu, K. Hagiwara, H. Itoh, M. Inoue, "Unified Total Synthesis of Five Bufadienolides," Org. Lett. in press.
    DOI: 10.1021/acs.orglett.0c03251

  • 2020/10/7

    Publications updated.
    Koichi Kamiya, Kensuke Miura, Hiroaki Itoh, M. Inoue, "Divergent Solid‐Phase Synthesis and Biological Evaluation of Yaku’amide B and Its Seven E/Z Isomers," Chem. Eur. J. in press.
    DOI: 10.1002/chem.202003858

  • 2020/10/2

    Publications updated.
    M. Nagatomo, K. Zhang, H. Fujino, M. Inoue, "Et3B/Et2AlCl/O2‐Mediated Radical Coupling Reaction between α‐Alkoxyacyl Tellurides and 2‐Hydroxybenzaldehyde Derivatives," Chem. Asian. J. in press.
    DOI: 10.1002/asia.202001090

  • 2020/10/1

    Publications updated.
    Y. Takada, H. Itoh, A. Paudel, S. Panthee, H. Hamamoto, K. Sekimizu, M. Inoue, "Discovery of gramicidin A analogues with altered activities by multidimensional screening of a one-bead-one-compound library," Nat. Commun. 2020, 11, 4935.
    DOI: 10.1038/s41467-020-18711-2

  • 2020/9/9

    Takumi Fukuda (G4) received Presentation Award at the 18th Symposium on Organic Chemistry -the Next Generation-. Title: "Convergent Total Synthesis of Hikizimycin"

  • 2020/8/6

    Publications updated.
    T. Fukuda, M. Nagatomo, M. Inoue, "Total Synthesis of Diospyrodin and Its Three Diastereomers," Org. Lett. in press.
    DOI: 10.1021/acs.orglett.0c02280

  • 2020/7/11

    Publications updated.
    K. Minagawa, D. Kamakura, K. Hagiwara, M. Inoue, "Construction of the ABCE-ring structure of talatisamine via decarboxylative radical cyclization," Tetrahedron in press.
    DOI: 10.1016/j.tet.2020.131385

  • 2020/7/8

    Dr. Haruka Fujino, a graduate from our laboratory, was chosen as one of the finalists of The Reaxys PhD Prize 2020. link

  • 2020/7/7

    Publications updated.
    H. Fujino, T. Fukuda, M. Nagatomo, M. Inoue, "Convergent Total Synthesis of Hikizimycin Enabled by Intermolecular Radical Addition to Aldehyde," J. Am. Chem. Soc. in press.
    DOI: 10.1021/jacs.0c06354

  • 2020/6/5

    Publications updated.
    M. Inoue, K. Tokumoto, T. Kaji, H. Itoh, "Design, Construction, and Screening of a One-Bead-One-Compound Library for Discovery of Potent Analogues of Antibiotic Lysocin E," MEDCHEM NEWS 2020, 30 (2), 84-88.

  • 2020/2/1

    Publications updated.
    J. Mao, H. Itoh, K. Sakurai, M. Inoue, "Phospholipid-Dependent Functions of a Macrocyclic Analogue of the Ion-Channel-Forming Antibiotic Gramicidin A," Chem. Pharm. Bull.2020, 68, 173.
    DOI: 10.1248/cpb.c19-00967

  • 2020/1/27

    Dr. Kamakura recieved a presentation award at 61st Symposium on the Chemistry of Natural Products. Title: Total Synthesis of Talatisamine

  • 2020/1/13

    Publications updated.
    H. Itoh, K. Miura, K. Kamiya, T. Yamashita, M. Inoue, "Solid‐Phase Total Synthesis of Yaku’amide B Enabled by Traceless Staudinger Ligation," Angew. Chem. Int. Ed. in press.
    DOI: 10.1002/anie.201916517